Factor IX (Christmas Factor) (Last Updated - 3/29/2005)

-involved in the intrinsic pathway
-gets activated to form Factor IXa via catalysis by Factor XIa & also via crossover from the extrinsic pathway via tissue factor (TF or Factor III) & Factor VIIa
-if pt. is deficient --> Hemophilia (Type B)
-1/2-Life:
     ~24 hrs.

-click here to view an image of the clotting cascade

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References:

Goodman & Gilman's: The Pharmacologic Basis Of Therapeutics - 10th Edition - 2001. Chapter 55.